veratridine (Alomone Labs)

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Alomone Labs veratridine
Effects of TTX analogues on the viability of mouse neuroblastoma cells, Neuro-2a, exposed to ouabain and <t>veratridine.</t> Cell viability vs TTXs concentration (data points are means ± SD) and estimated EC 50 values (means ± SD, n = 4). Symbols indicate (●) TTX ( 1 ), (■) 6- epi -11-deoxyTTX ( 2 ).

Effects of TTX analogues on the viability of mouse neuroblastoma cells, Neuro-2a, exposed to ouabain and <t>veratridine.</t> Cell viability vs TTXs concentration (data points are means ± SD) and estimated EC 50 values (means ± SD, n = 4). Symbols indicate (●) TTX ( 1 ), (■) 6- epi -11-deoxyTTX ( 2 ).

Veratridine, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 12 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/veratridine/Veratridine/pmc12954848-223-37-40
Average 94 stars, based on 12 article reviews

veratridine - by Bioz Stars, 2026-10

94/100 stars

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1) Product Images from "Identification of Deoxy- and epi -Tetrodotoxin Analogues from the Newt Cynops ensicauda popei Suggests Stepwise Oxidation in Terrestrial Tetrodotoxin Biosynthesis"

Article Title: Identification of Deoxy- and epi -Tetrodotoxin Analogues from the Newt Cynops ensicauda popei Suggests Stepwise Oxidation in Terrestrial Tetrodotoxin Biosynthesis

Journal: Journal of Natural Products

doi: 10.1021/acs.jnatprod.5c01546

Effects of TTX analogues on the viability of mouse neuroblastoma cells, Neuro-2a, exposed to ouabain and veratridine. Cell viability vs TTXs concentration (data points are means ± SD) and estimated EC 50 values (means ± SD, n = 4). Symbols indicate (●) TTX ( 1 ), (■) 6- epi -11-deoxyTTX ( 2 ).

Figure Legend Snippet: Effects of TTX analogues on the viability of mouse neuroblastoma cells, Neuro-2a, exposed to ouabain and veratridine. Cell viability vs TTXs concentration (data points are means ± SD) and estimated EC 50 values (means ± SD, n = 4). Symbols indicate (●) TTX ( 1 ), (■) 6- epi -11-deoxyTTX ( 2 ).

Techniques Used: Analogues, Concentration Assay

Concentration Assay:

Article Title: Long QT syndrome type 3 gain-of-function of Na v 1.5 increases ventricular fibroblasts proliferation and pro-fibrotic factors
Article Snippet: .. Fibroblasts were chronically treated with veratridine (1 μM) diluted in DMSO (final concentration of 0.001% - Alomone) from the beginning of cell culture (5 days before seeding in e-plate), or with tetrodotoxin (50 μM - TTX citrate - Tocris Bioscience), ranolazine (50 μM - Tocris Bioscience) or calcineurin autoinhibitory peptide diluted in media (iCaN - Tocris Bioscience - 10 μM), GW788388 (20 μM) diluted in DMSO (final concentration of 0.00003%), or YM244769 (Tocris Bioscience - 10 μM) diluted in DMSO (final concentration of 0.01%) from the beginning of the xCELLigence experiment (day 5 of culture). .. The two cell pellets were re-suspended together in 50 mL of DMEM medium (Dulbecco’s Modified Eagle Medium with 4.5 g/L of D-Glucose, 4 mM of L-Glutamine, and 1 mM of Pyruvate; Gibco #41966-094) supplemented with 10% of FCS, 1% of antibiotics (Penicillin, Streptomycin) and 2 mM of glutamin.

Article Title: Long QT syndrome type 3 gain-of-function of Na v 1.5 increases ventricular fibroblasts proliferation and pro-fibrotic factors.
Article Snippet: .. Veratridine, tetrodotoxin, ranolazine, GW788388, YM244769 and Calcineurin autoinhibitory peptide treatments Fibroblasts were chronically treated with veratridine (1 μM) diluted in DMSO (final concentration of 0.001% - Alomone) from the beginning of cell culture (5 days before seeding in e-plate), or with tetrodotoxin (50 μM - TTX citrate - Tocris Bioscience), ranolazine (50 μM - Tocris Bioscience) or calcineurin autoinhibitory peptide diluted in media (iCaN - Tocris Bioscience - 10 μM), GW788388 (20 μM) diluted in DMSO (final concentration of 0.00003%), or YM244769 (Tocris Bioscience - 10 μM) diluted in DMSO (final concentration of 0.01%) from the beginning of the xCELLigence experiment (day 5 of culture). ..

Cell Culture:

other:

Article Title: Ca V 1.2-dependent excitation-transcription coupling modulates nociception
Article Snippet: Stock solutions were prepared as indicated in parentheses of the following compounds: Autocamtide-2 Related Inhibitory Peptide (AIP, Calbiochem, #189480, 500 μM in dH2O), (S)-(-)-Bay K 8644 (BayK, Alomone Labs, #B-351, 50 mM in DMSO), Capsaicin (Cap, Sigma-Aldrich, #M2028, 10 mM in DMSO), Cyclosporin A (CsA, Tocris, #1101, 50 mM in DMSO), H-89 Dihydrochloride (H89, Tocris, #2910, 25 mM in DMSO), KN93 (Tocris, #1278; 20 mM in DMSO), Nifedipine (Nife, Tocris, #1075, 10 mM in DMSO), Nimodipine (Nimo, Tocris, #0600, 10 mM in DMSO), STO-609 (Tocris, #1551, 10 mM in DMSO), U0126 (Calbiochem, #662005, 50 mM in DMSO), Verapamil (VP, Alomone Labs, #V-100, 100 mM stock in dH2O), Veratridine (VT, Alomone Labs; #V-110; 50 mM stock in DMSO), ω-agatoxin IVA (Alomone Labs, #STA-500, 200 μM stock in 0.1% BSA), ω-conotoxin GVIA (Alomone Labs, # C-300, 1 mM stock in 0.1% BSA), ω-conotoxin MVIIC (Alomone Labs, #C-150, 300 μM stock in 0.1% BSA).

Article Title: Identification of Deoxy- and epi -Tetrodotoxin Analogues from the Newt Cynops ensicauda popei Suggests Stepwise Oxidation in Terrestrial Tetrodotoxin Biosynthesis
Article Snippet: Cultured cells were harvested using a trypsin/EDTA solution (0.05%/0.2%, w/v) in phosphate-buffered saline (PBS), and resuspended at a density of 5 × 10 5 cells/mL in growth medium (RPMI-1640, Sigma-Aldrich) containing 10 U/mL penicillin, 10 μg/mL streptomycin, and 10% v/v FBS.

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